We are looking for an ambitious and motivated postgraduate candidate to design a mathematical framework for understanding complex multicellular interactions in tissue development and regeneration. This project will use tools from dynamical systems theory, statistical physics/stochastic processes, and Bayesian inference. A particular focus will lie on finding distinguishing measurable features of particular interaction networks, and from these to generate predictions that could be tested in collaboration with experimental labs.
The successful applicant will be based in the group of Dr Linus Schumacher ( crm.ed.ac.uk/research/group/computational-biology-cell-populations) at the MRC Centre for Regenerative Medicine and will also be working closely with Dr Ramon Grima (grimagroup.bio.ed.ac.uk). The Schumacher group develops mathematical models of cell populations in development and regeneration, working closely with experimental collaborators with the long-term aim to formulate principles that apply to multiple biological systems, gain insight into misregulation in disease, and inform improvements to regenerative therapy. The Grima group has extensive expertise in the building and theoretical analysis of stochastic models of intracellular dynamics and cell-cell interactions.
For further details, see www.findaphd.com/phds/project/mathematical-modelling-of-multicellular-interactions-in-stem-cell-regulation-and-tissue-regeneration/?p101556